Robust imaging of hippocampal inner structure at 7T: in vivo acquisition protocol and methodological choices.
MAGMA
; 29(3): 475-89, 2016 Jun.
Article
em En
| MEDLINE
| ID: mdl-27138193
ABSTRACT
OBJECTIVE:
Motion-robust multi-slab imaging of hippocampal inner structure in vivo at 7T. MATERIALS ANDMETHODS:
Motion is a crucial issue for ultra-high resolution imaging, such as can be achieved with 7T MRI. An acquisition protocol was designed for imaging hippocampal inner structure at 7T. It relies on a compromise between anatomical details visibility and robustness to motion. In order to reduce acquisition time and motion artifacts, the full slab covering the hippocampus was split into separate slabs with lower acquisition time. A robust registration approach was implemented to combine the acquired slabs within a final 3D-consistent high-resolution slab covering the whole hippocampus. Evaluation was performed on 50 subjects overall, made of three groups of subjects acquired using three acquisition settings; it focused on three issues visibility of hippocampal inner structure, robustness to motion artifacts and registration procedure performance.RESULTS:
Overall, T2-weighted acquisitions with interleaved slabs proved robust. Multi-slab registration yielded high quality datasets in 96 % of the subjects, thus compatible with further analyses of hippocampal inner structure.CONCLUSION:
Multi-slab acquisition and registration setting is efficient for reducing acquisition time and consequently motion artifacts for ultra-high resolution imaging of the inner structure of the hippocampus.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Mapeamento Encefálico
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Imageamento por Ressonância Magnética
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Hipocampo
Tipo de estudo:
Prevalence_studies
/
Risk_factors_studies
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article