TreeQTL: hierarchical error control for eQTL findings.

ABSTRACT

UNLABELLED Commonly used multiplicity adjustments fail to control the error rate for reported findings in many expression quantitative trait loci (eQTL) studies. TreeQTL implements a hierarchical multiple testing procedure which allows control of appropriate error rates defined relative to a grouping of the eQTL hypotheses. AVAILABILITY AND IMPLEMENTATION The R package TreeQTL is available for download at http//bioinformatics.org/treeqtl CONTACT sabatti@stanford.edu SUPPLEMENTARY INFORMATION Supplementary data are available at Bioinformatics online.