[Prevalence of uterine anatomical anomalies in mexican women with recurrent pregnancy loss (RPL)]. / Prevalencia de las alteraciones anatómicas uterinas en mujeres mexicanas con pérdida gestacional recurrente (PGR).

ABSTRACT

INTRODUCTION: In Mexico, the information available about the prevalence of uterine anatomical anomalies as the direct and indirect cause of recurrent pregnancy loss (RPL) is limited. OBJECTIVE: To know the prevalence and types of uterine anatomical anomalies in Mexican women with RPL. METHODS: In a cross-sectional study, we included women attending a clinic for RPL from 2008 to 2013, with a history of three or more consecutive gestational losses, with the same couple and complete study protocol by factors. Altered anatomical factor was defined by any of the following diagnoses Müllerian malformations, submucosal myomas, uterine synechiae, endometrial polyp, and cervical weakness, confirmed by laparoscopy and hysteroscopy. RESULTS: We analyzed 188 women. The prevalence of anatomical anomalies was 41.5% (n = 78); the type of anatomical anomaly was cervical weakness 15.9% (n = 30), septate uterus 11.7% (n = 22), and uterine synechiae 9.6% (n = 18), endometrial polyps 1.6% (n = 3), bicornuate uterus 1.1% (n = 2), arcuate uterus 0.5% (n = 1), didelphic uterus 0.5% (n=1), and submucosal myoma 0.5% (n=1). We identified the anatomic factor as the unique cause of RPL in 35.6% (n = 67) of cases. CONCLUSIONS: The prevalence of altered anatomical factor in Mexican women with RPL is 41.5%; more frequent anomalies were cervical weakness, septate uterus, and uterine synechiae.