HOTf-Catalyzed, Solvent-Free Oxyarylation of Ynol Ethers and Thioethers.
J Org Chem
; 81(11): 4861-8, 2016 06 03.
Article
em En
| MEDLINE
| ID: mdl-27163354
ABSTRACT
A novel HOTf-catalyzed oxyarylation of ynol ethers and thioethers has been realized with aryl sulfoxides as the oxyarylating reagents, providing α-arylated esters or thioesters in good to excellent yields. Notably, all atoms of the starting materials were incorporated in the product (100% atom economy) and the reaction proceeded under very mild conditions. It was found that the reaction can be ran under air and that the best yields are obtained under solvent-free conditions.
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01-internacional
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MEDLINE
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article