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Radiolabeled hydroxamate-based matrix metalloproteinase inhibitors: How chemical modifications affect pharmacokinetics and metabolic stability.
Hugenberg, Verena; Hermann, Sven; Galla, Fabian; Schäfers, Michael; Wünsch, Bernhard; Kolb, Hartmuth C; Szardenings, Katrin; Lebedev, Artem; Walsh, Joseph C; Mocharla, Vani P; Gangadharmath, Umesh B; Kopka, Klaus; Wagner, Stefan.
Afiliação
  • Hugenberg V; Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149, Münster, Germany; European Institute for Molecular Imaging, University of Münster, Waldeyerstraße 15, D-48149, Münster, Germany. Electronic address: verena.hugenberg@gmx.de.
  • Hermann S; European Institute for Molecular Imaging, University of Münster, Waldeyerstraße 15, D-48149, Münster, Germany; DFG EXC 1003 Cluster of Excellence 'Cells in Motion', University of Münster, Münster, Germany.
  • Galla F; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, D-48149, Münster, Germany.
  • Schäfers M; Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149, Münster, Germany; European Institute for Molecular Imaging, University of Münster, Waldeyerstraße 15, D-48149, Münster, Germany; DFG EXC 1003 Cluster of Excellence 'Cells in Motion', Univer
  • Wünsch B; Institute of Pharmaceutical and Medicinal Chemistry, University of Münster, Corrensstraße 48, D-48149, Münster, Germany.
  • Kolb HC; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Szardenings K; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Lebedev A; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Walsh JC; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Mocharla VP; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Gangadharmath UB; Siemens Medical Solutions USA, Inc., 6140 Bristol Parkway, Culver City, CA, 90230, USA.
  • Kopka K; Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149, Münster, Germany.
  • Wagner S; Department of Nuclear Medicine, University Hospital Münster, Albert-Schweitzer-Campus 1, Building A1, D-48149, Münster, Germany.
Nucl Med Biol ; 43(7): 424-37, 2016 07.
Article em En | MEDLINE | ID: mdl-27179748
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Metaloproteinases de Matriz / Ácidos Hidroxâmicos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Metaloproteinases de Matriz / Ácidos Hidroxâmicos Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article