The high matrix acquisition technique for imaging of atherosclerotic plaque inflammation in fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography with time-of-flight: Phantom study.
J Nucl Cardiol
; 24(4): 1161-1170, 2017 08.
Article
em En
| MEDLINE
| ID: mdl-27197819
ABSTRACT
BACKGROUND:
Motion artifact and partial volume effect caused underestimation of coronary plaque inflammation. This study evaluated the high matrix acquisition technique using time-of-flight (TOF) positron emission tomography/computed tomography for imaging of atherosclerotic plaque inflammation with fluorine-18 fluorodeoxyglucose in small and moving phantoms. METHODS ANDRESULTS:
All images were reconstructed using a conventional algorithm without TOF (4 × 4 × 4 mm3 voxel size) and a high matrix algorithm with TOF (2 × 2 × 2 mm3 voxel size). Microsphere phantoms of 10, 7.9, 6.2, 5.0, and 4.0 mm diameters were acquired in 3-dimensional list-mode for 30 minutes. A heart phantom mimicking cardiac motion consisted of a hot spot simulating a plaque (φ 4 mm, φ 2 mm) on the outside of the left ventricle. In the microsphere and heart phantom study, visual discrimination, maximum activity, and target-to-background ratio using the high matrix algorithm with TOF were better than those using the conventional algorithm without TOF.CONCLUSION:
The high matrix algorithm with TOF improves detection of small targets in phantoms.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Processamento de Imagem Assistida por Computador
/
Imagens de Fantasmas
/
Fluordesoxiglucose F18
/
Placa Aterosclerótica
/
Tomografia por Emissão de Pósitrons combinada à Tomografia Computadorizada
/
Inflamação
Limite:
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article