Low-Molecular Weight Polyethylenimine Modified with Pluronic 123 and RGD- or Chimeric RGD-NLS Peptide: Characteristics and Transfection Efficacy of Their Complexes with Plasmid DNA.

Hu, Jing; Zhao, Wenfang; Liu, Kehai; Yu, Qian; Mao, Yuan; Lu, Zeyu; Zhang, Yaguang; Zhu, Manman

Hu, Jing; Zhao, Wenfang; Liu, Kehai; Yu, Qian; Mao, Yuan; Lu, Zeyu; Zhang, Yaguang; Zhu, Manman.

Afiliação

Hu J; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. 15821787592@163.com.
Zhao W; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. wfzhao0504@163.com.
Liu K; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. khliu@shou.edu.cn.
Yu Q; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. 15001970365@163.com.
Mao Y; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. 13262975153@163.com.
Lu Z; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. m18701881332@163.com.
Zhang Y; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. edwarddo@163.com.
Zhu M; Department of Biopharmaceutics, College of Food Science and Technology, Shanghai Ocean University, Shanghai 201306, China. zhu_manman7526@163.com.

Molecules ; 21(5)2016 May 18.

Article em En | MEDLINE | ID: mdl-27213305

Assuntos

Técnicas de Transferência de Genes; Terapia Genética/métodos; Sinais de Localização Nuclear/genética; Oligopeptídeos/genética; Polietilenoimina/química; DNA; Eletroforese em Gel de Ágar; Proteínas de Fluorescência Verde; Células HeLa; Humanos; Peso Molecular; Nanopartículas/química; Nanopartículas/uso terapêutico; Sinais de Localização Nuclear/química; Sinais de Localização Nuclear/uso terapêutico; Oligopeptídeos/química; Oligopeptídeos/uso terapêutico; Plasmídeos/química; Plasmídeos/genética; Polietilenoimina/uso terapêutico; Polímeros/química; Polímeros/uso terapêutico; Transfecção/métodos

Palavras-chave

RGD; nuclear localization signal; physico-chemical properties; polycations; transfection efficiency

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Polietilenoimina / Terapia Genética / Técnicas de Transferência de Genes / Sinais de Localização Nuclear Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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