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Influence of particle size on the in vivo potency of lipid nanoparticle formulations of siRNA.
Chen, Sam; Tam, Yuen Yi C; Lin, Paulo J C; Sung, Molly M H; Tam, Ying K; Cullis, Pieter R.
Afiliação
  • Chen S; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Tam YYC; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Lin PJC; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada; Acuitas Therapeutics, 2714 West 31st Avenue, Vancouver, British Columbia V6L 2A1, Canada.
  • Sung MMH; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada.
  • Tam YK; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada; Acuitas Therapeutics, 2714 West 31st Avenue, Vancouver, British Columbia V6L 2A1, Canada.
  • Cullis PR; Department of Biochemistry and Molecular Biology, University of British Columbia, 2350 Health Sciences Mall, Vancouver, British Columbia V6T 1Z3, Canada. Electronic address: pieterc@mail.ubc.ca.
J Control Release ; 235: 236-244, 2016 08 10.
Article em En | MEDLINE | ID: mdl-27238441
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Interferente Pequeno / Nanopartículas / Lipídeos Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Interferente Pequeno / Nanopartículas / Lipídeos Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article