Role of capsaicin-sensitive nerves and tachykinins in mast cell tryptase-induced inflammation of murine knees.

Borbély, Éva; Sándor, Katalin; Markovics, Adrienn; Kemény, Ágnes; Pintér, Erika; Szolcsányi, János; Quinn, John P; McDougall, Jason J; Helyes, Zsuzsanna

Borbély, Éva; Sándor, Katalin; Markovics, Adrienn; Kemény, Ágnes; Pintér, Erika; Szolcsányi, János; Quinn, John P; McDougall, Jason J; Helyes, Zsuzsanna.

Afiliação

Borbély É; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pecs, 7624, Hungary.
Sándor K; János Szentágothai Research Centre, Molecular Pharmacology Research Group, Centre for Neuroscience, University of Pécs, Pecs, Hungary.
Markovics A; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pecs, 7624, Hungary.
Kemény Á; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pecs, 7624, Hungary.
Pintér E; János Szentágothai Research Centre, Molecular Pharmacology Research Group, Centre for Neuroscience, University of Pécs, Pecs, Hungary.
Szolcsányi J; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pecs, 7624, Hungary.
Quinn JP; János Szentágothai Research Centre, Molecular Pharmacology Research Group, Centre for Neuroscience, University of Pécs, Pecs, Hungary.
McDougall JJ; Department of Pharmacology and Pharmacotherapy, Medical School, University of Pécs, Szigeti u. 12, Pecs, 7624, Hungary.
Helyes Z; János Szentágothai Research Centre, Molecular Pharmacology Research Group, Centre for Neuroscience, University of Pécs, Pecs, Hungary.

Inflamm Res ; 65(9): 725-36, 2016 Sep.

Article em En | MEDLINE | ID: mdl-27251170

Assuntos

Artrite/induzido quimicamente; Edema/induzido quimicamente; Hiperalgesia/induzido quimicamente; Inflamação Neurogênica/induzido quimicamente; Dor/induzido quimicamente; Triptases; Animais; Artrite/metabolismo; Peptídeo Relacionado com Gene de Calcitonina/metabolismo; Capsaicina; Citocinas/metabolismo; Edema/metabolismo; Edema/patologia; Hiperalgesia/metabolismo; Hiperalgesia/patologia; Articulação do Joelho/metabolismo; Articulação do Joelho/patologia; Masculino; Camundongos Endogâmicos C57BL; Camundongos Knockout; Inflamação Neurogênica/metabolismo; Inflamação Neurogênica/patologia; Dor/metabolismo; Dor/patologia; Precursores de Proteínas/genética; Receptor PAR-2/metabolismo; Receptores da Neurocinina-1/genética; Substância P/metabolismo; Canais de Cátion TRPV/genética; Taquicininas/genética; Tato

Palavras-chave

Arthritis; Capsaicin-sensitive sensory nerves; Inflammation; Oedema; Pain; Synovial microcirculation

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Artrite / Inflamação Neurogênica / Edema / Triptases / Hiperalgesia Tipo de estudo: Diagnostic_studies Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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