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Novel analogs of allopregnanolone show improved efficiency and specificity in neuroprotection and stimulation of proliferation.
Karout, Mona; Miesch, Michel; Geoffroy, Philippe; Kraft, Stephanie; Hofmann, Hans-Dieter; Mensah-Nyagan, Ayikoe Guy; Kirsch, Matthias.
Afiliação
  • Karout M; Institute of Anatomy and Cell Biology, Department of Neuroanatomy, ZfN, Faculty of Medicine, University of Freiburg, Albertstr. 23, D-79104, Freiburg, Germany.
  • Miesch M; Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, INSERM U1119, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France.
  • Geoffroy P; Laboratoire de Chimie Organique Synthétique, UMR 7177, Institut de Chimie de l'Université de Strasbourg, Strasbourg, France.
  • Kraft S; Laboratoire de Chimie Organique Synthétique, UMR 7177, Institut de Chimie de l'Université de Strasbourg, Strasbourg, France.
  • Hofmann HD; Institute of Anatomy and Cell Biology, Department of Neuroanatomy, ZfN, Faculty of Medicine, University of Freiburg, Albertstr. 23, D-79104, Freiburg, Germany.
  • Mensah-Nyagan AG; Institute of Anatomy and Cell Biology, Department of Neuroanatomy, ZfN, Faculty of Medicine, University of Freiburg, Albertstr. 23, D-79104, Freiburg, Germany.
  • Kirsch M; Biopathologie de la Myéline, Neuroprotection et Stratégies Thérapeutiques, INSERM U1119, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France.
J Neurochem ; 139(5): 782-794, 2016 12.
Article em En | MEDLINE | ID: mdl-27256158
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pregnanolona / Fármacos Neuroprotetores / Proliferação de Células Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pregnanolona / Fármacos Neuroprotetores / Proliferação de Células Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article