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The crystal structure of the major pneumococcal autolysin LytA in complex with a large peptidoglycan fragment reveals the pivotal role of glycans for lytic activity.
Sandalova, Tatyana; Lee, Mijoon; Henriques-Normark, Birgitta; Hesek, Dusan; Mobashery, Shahriar; Mellroth, Peter; Achour, Adnane.
Afiliação
  • Sandalova T; Science for Life Laboratory, Department of Medicine Solna, Karolinska Institutet, and Department of Infectious Diseases, Karolinska University Hospital, Solna, Stockholm, SE, 17176, Sweden.
  • Lee M; Departments of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
  • Henriques-Normark B; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 171 77, Sweden.
  • Hesek D; Department of Clinical Microbiology, Karolinska University Hospital, Solna, Stockholm, 17176, Sweden.
  • Mobashery S; Departments of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
  • Mellroth P; Departments of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, IN, 46556, USA.
  • Achour A; Department of Microbiology, Tumor and Cell Biology, Karolinska Institutet, Stockholm, 171 77, Sweden. peter.mellroth@ki.se.
Mol Microbiol ; 101(6): 954-67, 2016 09.
Article em En | MEDLINE | ID: mdl-27273793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptidoglicano / N-Acetil-Muramil-L-Alanina Amidase Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptidoglicano / N-Acetil-Muramil-L-Alanina Amidase Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article