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Rifaximin, a non-absorbable antibiotic, inhibits the release of pro-angiogenic mediators in colon cancer cells through a pregnane X receptor-dependent pathway.
Esposito, Giuseppe; Gigli, Stefano; Seguella, Luisa; Nobile, Nicola; D'Alessandro, Alessandra; Pesce, Marcella; Capoccia, Elena; Steardo, Luca; Cirillo, Carla; Cuomo, Rosario; Sarnelli, Giovanni.
Afiliação
  • Esposito G; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • Gigli S; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • Seguella L; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • Nobile N; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • D'Alessandro A; Department of Clinical Medicine and Surgery, 'Federico II' University of Naples, I-80131 Naples, Italy.
  • Pesce M; Department of Clinical Medicine and Surgery, 'Federico II' University of Naples, I-80131 Naples, Italy.
  • Capoccia E; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • Steardo L; Department of Physiology and Pharmacology, 'Vittorio Erspamer', La Sapienza University of Rome, I-00185 Rome, Italy.
  • Cirillo C; Laboratory for Enteric NeuroScience (LENS), Translational Research Center for Gastrointestinal Disorders (TARGID), University of Leuven, 3000 Leuven, Belgium.
  • Cuomo R; Department of Clinical Medicine and Surgery, 'Federico II' University of Naples, I-80131 Naples, Italy.
  • Sarnelli G; Department of Clinical Medicine and Surgery, 'Federico II' University of Naples, I-80131 Naples, Italy.
Int J Oncol ; 49(2): 639-45, 2016 Aug.
Article em En | MEDLINE | ID: mdl-27279570
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifamicinas / Receptores de Esteroides / Neoplasias do Colo / Inflamação / Neovascularização Patológica Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Rifamicinas / Receptores de Esteroides / Neoplasias do Colo / Inflamação / Neovascularização Patológica Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article