Integrating multiple immunogenetic data sources for feature extraction and mining somatic hypermutation patterns: the case of "towards analysis" in chronic lymphocytic leukaemia.

Kavakiotis, Ioannis; Xochelli, Aliki; Agathangelidis, Andreas; Tsoumakas, Grigorios; Maglaveras, Nicos; Stamatopoulos, Kostas; Hadzidimitriou, Anastasia; Vlahavas, Ioannis; Chouvarda, Ioanna

Kavakiotis, Ioannis; Xochelli, Aliki; Agathangelidis, Andreas; Tsoumakas, Grigorios; Maglaveras, Nicos; Stamatopoulos, Kostas; Hadzidimitriou, Anastasia; Vlahavas, Ioannis; Chouvarda, Ioanna.

Afiliação

Kavakiotis I; Department of Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece. ikavak@csd.auth.gr.
Xochelli A; Institute of Applied Biosciences, CERTH, Thessaloniki, Greece.
Agathangelidis A; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.
Tsoumakas G; Division of Molecular Oncology and Department of Onco-Hematology, San Raffaele Scientific Institute, Milan, Italy.
Maglaveras N; Department of Informatics, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Stamatopoulos K; Institute of Applied Biosciences, CERTH, Thessaloniki, Greece.
Hadzidimitriou A; Lab of Computing and Medical Informatics, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Vlahavas I; Institute of Applied Biosciences, CERTH, Thessaloniki, Greece.
Chouvarda I; Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

BMC Bioinformatics ; 17 Suppl 5: 173, 2016 Jun 06.

Article em En | MEDLINE | ID: mdl-27295298

Assuntos

Imunogenética/métodos; Leucemia Linfocítica Crônica de Células B/genética; Hipermutação Somática de Imunoglobulina/genética; Adulto; Bases de Dados Genéticas; Feminino; Mutação em Linhagem Germinativa; Humanos; Região Variável de Imunoglobulina/genética; Imunoglobulinas/genética; Leucemia Linfocítica Crônica de Células B/patologia

Palavras-chave

CLL; Chronic lymphocytic leukaemia; Data integration; Feature extraction; List aggregation; Mutation patterns, somatic hypermutation; SHM

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Linfocítica Crônica de Células B / Hipermutação Somática de Imunoglobulina / Imunogenética Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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