Duplications of SLC1A3: Associated with ADHD and autism.
Eur J Med Genet
; 59(8): 373-6, 2016 Aug.
Article
em En
| MEDLINE
| ID: mdl-27296938
ABSTRACT
We report four patients with a similar gain in 5p13.2 encompassing a single gene SLC1A3. Behavioural problems resembling ADHD and/or autism-like features are observed which is in line with the glial glutamate transporter role of SLC1A3. We consider an association between SLC1A3 and the behavioural problems which can also be considered a contributing factor to behavioural problems in larger duplications overlapping the 5p13 microduplication syndrome region.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transtorno do Deficit de Atenção com Hiperatividade
/
Transtorno Autístico
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Duplicação Gênica
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Transportador 1 de Aminoácido Excitatório
Tipo de estudo:
Prognostic_studies
/
Risk_factors_studies
Limite:
Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article