Type I interferon promotes alveolar epithelial type II cell survival during pulmonary Streptococcus pneumoniae infection and sterile lung injury in mice.

Maier, Barbara B; Hladik, Anastasiya; Lakovits, Karin; Korosec, Ana; Martins, Rui; Kral, Julia B; Mesteri, Ildiko; Strobl, Birgit; Müller, Mathias; Kalinke, Ulrich; Merad, Miriam; Knapp, Sylvia

Maier, Barbara B; Hladik, Anastasiya; Lakovits, Karin; Korosec, Ana; Martins, Rui; Kral, Julia B; Mesteri, Ildiko; Strobl, Birgit; Müller, Mathias; Kalinke, Ulrich; Merad, Miriam; Knapp, Sylvia.

Afiliação

Maier BB; CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Hladik A; Laboratory of Infection Biology, Department of Medicine I, Medical University, Vienna, Austria.
Lakovits K; Laboratory of Infection Biology, Department of Medicine I, Medical University, Vienna, Austria.
Korosec A; Laboratory of Infection Biology, Department of Medicine I, Medical University, Vienna, Austria.
Martins R; CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Kral JB; Laboratory of Infection Biology, Department of Medicine I, Medical University, Vienna, Austria.
Mesteri I; CeMM - Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.
Strobl B; Laboratory of Infection Biology, Department of Medicine I, Medical University, Vienna, Austria.
Müller M; Center for Physiology and Pharmacology, Institute for Physiology, Medical University of Vienna, Vienna, Austria.
Kalinke U; Pathology Überlingen, Überlingen, Germany.
Merad M; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.
Knapp S; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.

Eur J Immunol ; 46(9): 2175-86, 2016 09.

Article em En | MEDLINE | ID: mdl-27312374

Assuntos

Células Epiteliais Alveolares/metabolismo; Sobrevivência Celular; Interferon Tipo I/metabolismo; Lesão Pulmonar/etiologia; Lesão Pulmonar/metabolismo; Pneumonia Pneumocócica/etiologia; Pneumonia Pneumocócica/metabolismo; Animais; Modelos Animais de Doenças; Feminino; Imunomodulação; Lesão Pulmonar/patologia; Macrófagos Alveolares/imunologia; Macrófagos Alveolares/metabolismo; Camundongos; Camundongos Knockout; Pneumonia Pneumocócica/patologia; Receptor de Interferon alfa e beta/metabolismo; Transdução de Sinais; Streptococcus pneumoniae

Palavras-chave

Acute lung injury; Alveolar epithelial cells; Epithelial barrier; Pneumococcal pneumonia; Type I interferon

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pneumonia Pneumocócica / Interferon Tipo I / Sobrevivência Celular / Lesão Pulmonar / Células Epiteliais Alveolares Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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