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Targeting MTHFD2 in acute myeloid leukemia.
Pikman, Yana; Puissant, Alexandre; Alexe, Gabriela; Furman, Andrew; Chen, Liying M; Frumm, Stacey M; Ross, Linda; Fenouille, Nina; Bassil, Christopher F; Lewis, Caroline A; Ramos, Azucena; Gould, Joshua; Stone, Richard M; DeAngelo, Daniel J; Galinsky, Ilene; Clish, Clary B; Kung, Andrew L; Hemann, Michael T; Vander Heiden, Matthew G; Banerji, Versha; Stegmaier, Kimberly.
Afiliação
  • Pikman Y; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Puissant A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Institut National de la Santé et de la Recherche Medicale U1065, Team 2, C3M, 06204 Nice, France.
  • Alexe G; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142 Bioinformatics Graduate Program, Boston
  • Furman A; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Chen LM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Frumm SM; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Ross L; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Fenouille N; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Bassil CF; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215.
  • Lewis CA; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Ramos A; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Gould J; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142.
  • Stone RM; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • DeAngelo DJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Galinsky I; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215.
  • Clish CB; Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142.
  • Kung AL; Department of Pediatrics, Columbia University Medical Center, New York, NY 10032.
  • Hemann MT; Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Technology, Cambridge, MA 02142.
  • Vander Heiden MG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142 Koch Institute for Integrative Cancer Research at Massachusetts Institute of Technology, Massachusetts Institute of Tech
  • Banerji V; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Research Institute of Oncology and Hematology at CancerCare Manitoba and the University of Manitoba, Winnipeg R3E OV9, Manitoba, Canada.
  • Stegmaier K; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02215 Division of Hematology/Oncology, Boston Children's Hospital, Boston, MA 02215 Broad Institute of Massachusetts Institute of Technology and Harvard University, Cambridge, MA 02142 kimberly_stegmaier@dfci.harvard.edu.
J Exp Med ; 213(7): 1285-306, 2016 06 27.
Article em En | MEDLINE | ID: mdl-27325891
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Enzimológica da Expressão Gênica / Regulação Leucêmica da Expressão Gênica / Proteínas Proto-Oncogênicas c-myc / Ciclo do Ácido Cítrico / Meteniltetra-Hidrofolato Cicloidrolase Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucemia Mieloide Aguda / Regulação Enzimológica da Expressão Gênica / Regulação Leucêmica da Expressão Gênica / Proteínas Proto-Oncogênicas c-myc / Ciclo do Ácido Cítrico / Meteniltetra-Hidrofolato Cicloidrolase Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article