Novel Insights into Cardiovascular Regulation in Patients with Chronic Mountain Sickness.
Adv Exp Med Biol
; 903: 83-100, 2016.
Article
em En
| MEDLINE
| ID: mdl-27343090
ABSTRACT
Studies of high-altitude populations, and in particular of maladapted subgroups, may provide important insight into underlying mechanisms involved in the pathogenesis of hypoxemia-related disease in general. Chronic mountain sickness (CMS) is a major public health problem in mountainous regions of the world affecting many millions of high-altitude dwellers. It is characterized by exaggerated chronic hypoxemia, erythrocytosis, and mild pulmonary hypertension. In later stages these patients often present with right heart failure and are predisposed to systemic cardiovascular disease, but the underlying mechanisms are poorly understood. Here, we present recent new data providing insight into underlying mechanisms that may cause these complications.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sistema Cardiovascular
/
Doença da Altitude
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article