Perfusion magnetic resonance imaging provides additional information as compared to anatomical imaging for decision-making in vestibular schwannoma.
Eur J Radiol Open
; 3: 127-33, 2016.
Article
em En
| MEDLINE
| ID: mdl-27366777
ABSTRACT
OBJECTIVE:
The added value of perfusion MRI for decision-making in vestibular schwannoma (VS) patients is unknown. MRI offers two perfusionmethods:
the first employing contrast agent (dynamic susceptibility contrast (DSC)-MRI) that provides information on cerebral blood volume (CBV) and cerebral blood flow (CBF), the second by magnetic labeling of blood (arterial spin labeling (ASL)-MRI), providing CBF-images. The goal of the current study is to investigate whether DSC and ASL perfusion MRI provides complimentary information to current anatomical imaging in treatment selection process of VS.METHODS:
Nine patients with growing VS with extrameatal diameter >9 mm were included (>2 mm/year and 20% volume expansion/year) and one patient with 23 mm extrameatal VS without growth. DSC and ASL perfusion MRI were obtained on 3 T MRI. Perfusion in VS was scored as hyperintense, hypointense or isointense compared to the contralateral region.RESULTS:
Seven patients showed hyperintense signal on DSC and ASL sequences. Three patients showed iso- or hypointense signal on at least one perfusion map (1 patient hypointense on both DSC-MRI and ASL; 1 patient isointense on DSC-CBF; 1 patient isointense on ASL). All patients showed enhancement on post-contrast T1 anatomical scan.CONCLUSION:
Perfusion MR provides additional information compared to anatomical imaging for decision-making in VS.
AAO-HNS, American Academy of Otolaryngology-Head and Neck Surgery; ASL, arterial spin labeling; CA, contrast agent; CBF, cerebral blood flow; CBV, cerebral blood volume; DSC, dynamic susceptibility contrast; Decision making; Dynamic susceptibility contrast (DSC) and arterial spin labeling (ASL); EPI, echo planar imaging; FA, flip angle; FOV, field of view; Gd, gadolinium; MR, magnetic resonance; MRI, magnetic resonance imaging; PCASL, pseudo-continuous arterial spin labeling; Perfusion weighted MR; RF, radiofrequency; SNR, signal to noise ratio; TE, echo time; TR, repetition time; VS, vestibular schwannoma; Vestibular schwannoma; rCBV, relative CBV
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Tipo de estudo:
Prognostic_studies
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article