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Cartilage-Specific Knockout of the Mechanosensory Ion Channel TRPV4 Decreases Age-Related Osteoarthritis.
O'Conor, Christopher J; Ramalingam, Sendhilnathan; Zelenski, Nicole A; Benefield, Halei C; Rigo, Isaura; Little, Dianne; Wu, Chia-Lung; Chen, Di; Liedtke, Wolfgang; McNulty, Amy L; Guilak, Farshid.
Afiliação
  • O'Conor CJ; Department of Pathology &Immunology, Washington University in St. Louis, Missouri, 63110, USA.
  • Ramalingam S; UNC/NCSU Joint Department of Biomedical Engineering, UNC School of Medicine, Chapel Hill, NC 27599, USA.
  • Zelenski NA; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • Benefield HC; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • Rigo I; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • Little D; UNC/NCSU Joint Department of Biomedical Engineering, UNC School of Medicine, Chapel Hill, NC 27599, USA.
  • Wu CL; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • Chen D; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • Liedtke W; Department of Orthopaedic Surgery, Duke University Medical Center, Durham NC 27710, USA.
  • McNulty AL; Department of Orthopaedic Surgery, Washington University in St. Louis, Missouri, 63110, USA.
  • Guilak F; Shriners Hospitals for Children - St. Louis, St. Louis, Missouri 63110, USA.
Sci Rep ; 6: 29053, 2016 07 08.
Article em En | MEDLINE | ID: mdl-27388701

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Envelhecimento / Cartilagem Articular / Condrócitos / Mecanotransdução Celular / Canais de Cátion TRPV Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Osteoartrite / Envelhecimento / Cartilagem Articular / Condrócitos / Mecanotransdução Celular / Canais de Cátion TRPV Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article