The "Ram's Horns Sign": A Case Report of an Unusual Side Effect of OnabotulinumtoxinA in a Chronic Migraine Patient.
Headache
; 56(10): 1656-1658, 2016 Nov.
Article
em En
| MEDLINE
| ID: mdl-27393616
ABSTRACT
OnabotulinumtoxinA (BoNT-A) has been reported as an effective prophylactic treatment for chronic migraine to reduce disease severity improving health-related quality of life. However, BoNT-A, due to its activity on either the injected or adjacent muscles of the upper face, may induce well-known side-effects, such as the eyebrow or eyelid ptosis. However, unusual muscular side effects, related to the neurotoxic mechanism, may also arise. We describe the clinical case of a 55-year-old male patient who has been treated for chronic migraine by the injection of BoNT-A, according to the PREEMPT protocol. Two weeks later, the patient developed two symmetrical bumps on the upper part of the forehead similar to the horns of a ram. We report, for the first time, this peculiar BoNT-A side effect and suggest that the injection of additional BoNT-A doses in the upper medial frontal fibers, for each side, can normalize the forehead shape over two weeks.
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Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Dermatopatias
/
Toxinas Botulínicas Tipo A
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Inibidores da Liberação da Acetilcolina
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Transtornos de Enxaqueca
Tipo de estudo:
Guideline
Limite:
Humans
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Male
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Middle aged
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article