Comprehensive analysis of BRCA1 and BRCA2 germline mutations in a large cohort of 5931 Chinese women with breast cancer.

Zhang, Juan; Sun, Jie; Chen, Jiuan; Yao, Lu; Ouyang, Tao; Li, Jinfeng; Wang, Tianfeng; Fan, Zhaoqing; Fan, Tie; Lin, Benyao; Xie, Yuntao

Zhang, Juan; Sun, Jie; Chen, Jiuan; Yao, Lu; Ouyang, Tao; Li, Jinfeng; Wang, Tianfeng; Fan, Zhaoqing; Fan, Tie; Lin, Benyao; Xie, Yuntao.

Afiliação

Zhang J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Sun J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Chen J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Yao L; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Ouyang T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Li J; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Wang T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Fan Z; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Fan T; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Lin B; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China.
Xie Y; Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education/Beijing), Breast Center, Peking University Cancer Hospital & Institute, Beijing, 100142, People's Republic of China. zlxyt2@bjmu.edu.cn.

Breast Cancer Res Treat ; 158(3): 455-62, 2016 08.

Article em En | MEDLINE | ID: mdl-27393621

Assuntos

Povo Asiático/genética; Proteína BRCA1/genética; Proteína BRCA2/genética; Neoplasias da Mama/genética; Mutação em Linhagem Germinativa; Adulto; Idade de Início; Idoso; China; Estudos de Coortes; Feminino; Predisposição Genética para Doença; Humanos; Pessoa de Meia-Idade; Mutação; Prevalência

Palavras-chave

BRCA1/2 mutation; Breast cancer; Chinese women; Prevalence

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Mutação em Linhagem Germinativa / Proteína BRCA1 / Proteína BRCA2 / Povo Asiático Tipo de estudo: Etiology_studies / Guideline / Incidence_studies / Observational_studies / Prevalence_studies / Risk_factors_studies Limite: Adult / Aged / Female / Humans / Middle aged País/Região como assunto: Asia Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google