Effect of antituberculosis treatment on CYP2C19 enzyme activity in genetically polymorphic South Indian Tamilian population.

Xavier, Alphienes Stanley; Kumar, Saka Vinod; Sundaram, Rajan; Francis, Jose; Shewade, Deepak Gopal

Xavier, Alphienes Stanley; Kumar, Saka Vinod; Sundaram, Rajan; Francis, Jose; Shewade, Deepak Gopal.

Afiliação

Xavier AS; Department of Clinical Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry Union territory, India, 605 006.
Kumar SV; Department of Pulmonary Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry Union territory, India, 605 006.
Sundaram R; Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry Union territory, India, 605 006.
Francis J; Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry Union territory, India, 605 006.
Shewade DG; Department of Pharmacology, Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER), Puducherry Union territory, India, 605 006.

Fundam Clin Pharmacol ; 30(6): 607-615, 2016 Dec.

Article em En | MEDLINE | ID: mdl-27393733

Assuntos

Antituberculosos/uso terapêutico; Povo Asiático/genética; Citocromo P-450 CYP2C19/genética; Polimorfismo Genético/genética; Adulto; Feminino; Genótipo; Humanos; Hidroxilação/genética; Masculino

Palavras-chave

CYP2C19; drug interaction; enzyme induction; omeprazole; tuberculosis

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Povo Asiático / Citocromo P-450 CYP2C19 / Antituberculosos Tipo de estudo: Prognostic_studies Limite: Adult / Female / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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