Visible-Light Microscopic Discovery of Up to 150 µm Long Helical Amyloid Fibrils Built of the Dodecapeptide H-(Val-Ala-Leu)<sub>4</sub> -OH and of Decapeptides Derived from Insulin.

Swiontek, Monika; Kaminski, Zbigniew J; Kolesinska, Beata; Seebach, Dieter

Visible-Light Microscopic Discovery of Up to 150 µm Long Helical Amyloid Fibrils Built of the Dodecapeptide H-(Val-Ala-Leu)₄ -OH and of Decapeptides Derived from Insulin.

Swiontek, Monika; Kaminski, Zbigniew J; Kolesinska, Beata; Seebach, Dieter.

Afiliação

Swiontek M; Institute of Organic Chemistry, Technical University of Lodz, Zeromskiego 116, PL-90-924, Lodz.
Kaminski ZJ; Institute of Organic Chemistry, Technical University of Lodz, Zeromskiego 116, PL-90-924, Lodz.
Kolesinska B; Institute of Organic Chemistry, Technical University of Lodz, Zeromskiego 116, PL-90-924, Lodz. beata.kolesinska@p.lodz.pl.
Seebach D; Laboratorium für Organische Chemie, Departement Chemie und Angewandte Biowissenschaften, ETH-Zürich, Hönggerberg HCI, Vladimir-Prelog-Weg 3, CH-8093, Zürich. seebach@org.chem.ethz.ch.

Chem Biodivers ; 13(9): 1111-1117, 2016 Sep.

Article em En | MEDLINE | ID: mdl-27459320

Assuntos

Amiloide/química; Insulina/química; Luz; Microscopia; Peptídeos/química; Concentração de Íons de Hidrogênio; Conformação Molecular; Agregados Proteicos; Conformação Proteica

Palavras-chave

Amyloids; Fibrils; Peptide aggregation; Self-assembly; µm-size helical superstructures

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Peptídeos / Amiloide / Insulina / Luz / Microscopia Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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