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A convergent approach to side-chain homologated derivatives of 1α,25-dihydroxyergocalciferol.
Vinhas, Silvia; Vázquez, Socorro; Rodríguez-Borges, J E; Sigüeiro, Rita.
Afiliação
  • Vinhas S; Department of Organic Chemistry, Laboratorio "Ignacio Ribas", University of Santiago de Compostela, Avda Ciencias s/n, 15782 Santiago de Compostela, Spain; Department of Chemistry and Biochemistry, UCIBIO/REQUIMTE, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
  • Vázquez S; Department of Organic Chemistry, Laboratorio "Ignacio Ribas", University of Santiago de Compostela, Avda Ciencias s/n, 15782 Santiago de Compostela, Spain.
  • Rodríguez-Borges JE; Department of Chemistry and Biochemistry, UCIBIO/REQUIMTE, Rua do Campo Alegre 687, 4169-007 Porto, Portugal.
  • Sigüeiro R; Department of Organic Chemistry, Laboratorio "Ignacio Ribas", University of Santiago de Compostela, Avda Ciencias s/n, 15782 Santiago de Compostela, Spain. Electronic address: rita.sigueiro@usc.es.
J Steroid Biochem Mol Biol ; 173: 83-85, 2017 10.
Article em En | MEDLINE | ID: mdl-27473560
ABSTRACT
As part of our program on search for vitamin D analogs with selective biological properties, such as low or negligible calcemic action, we describe here an efficient and versatile synthetic approach to derivatives of 1α,25-dihydroxyvitamin D2 with homologated side-chains and substitution at C24 for biological evaluation.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitaminas / Ergocalciferóis / Técnicas de Química Sintética Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Vitaminas / Ergocalciferóis / Técnicas de Química Sintética Idioma: En Ano de publicação: 2017 Tipo de documento: Article