[New Progress of MALDI-TOF-IMS in the Study of Proteomics].
Fa Yi Xue Za Zhi
; 32(2): 126-30, 2016 Apr.
Article
em Zh
| MEDLINE
| ID: mdl-27501686
Matrix-assisted laser desorption/ionization time-of-flight imaging mass spectrometry (MALDI-TOF-IMS) has been a classical technique for studying proteomics in present and a tool for analyzing the distribution of proteins and small molecules within biological tissue sections. MALDI-TOF-IMS can analyze multiple unknown compounds in biological tissue sections simultaneously through a single measurement which can obtain molecule imaging of the tissue while maintaining the integrity of cellular and molecules in tissue. In recent years, imaging mass spectrometry technique develops relatively quickly in all biomedical domain. This paper based on the relevant data and reviews the present developing level of MALDI-TOF-IMS, the principle of imaging mass spectrometry, methology and the prospect in forensic pathology.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Espectrometria de Massas por Ionização e Dessorção a Laser Assistida por Matriz
/
Proteômica
/
Ciências Forenses
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
/
Male
Idioma:
Zh
Ano de publicação:
2016
Tipo de documento:
Article