CNTF-ACM promotes mitochondrial respiration and oxidative stress in cortical neurons through upregulating L-type calcium channel activity.

Sun, Meiqun; Liu, Hongli; Xu, Huanbai; Wang, Hongtao; Wang, Xiaojing

Sun, Meiqun; Liu, Hongli; Xu, Huanbai; Wang, Hongtao; Wang, Xiaojing.

Afiliação

Sun M; Department of Histology and Embryology, Bengbu Medical College, Bengbu, Anhui, China.
Liu H; Department of Gynecological Oncology, The First Affiliated Hospital of Bengbu Medical College, Bengbu, Anhui, China.
Xu H; Department of Endocrinology and Metabolism, Shanghai Jiaotong University Affiliated First People's Hospital, Shanghai, China.
Wang H; Department of Immunology, Bengbu Medical College, Bengbu, Anhui, China.
Wang X; Department of Respiration, Anhui Clinical and Preclinical Key Laboratory of Respiratory Disease, The First Affiliated Hospital of Bengbu Medical College, No. 287 Changhuai Road, Bengbu, 233000, Anhui, China. wangxiaojing8888@163.com.

Mol Cell Biochem ; 420(1-2): 195-206, 2016 Sep.

Article em En | MEDLINE | ID: mdl-27514537

Assuntos

Canais de Cálcio Tipo L/metabolismo; Córtex Cerebral/metabolismo; Meios de Cultivo Condicionados/farmacologia; Mitocôndrias/metabolismo; Neurônios/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Animais; Córtex Cerebral/citologia; Potencial da Membrana Mitocondrial/efeitos dos fármacos; Neurônios/citologia; Ratos; Ratos Sprague-Dawley; Espécies Reativas de Oxigênio/metabolismo

Palavras-chave

Astrocyte; CNTF; CNTF-ACM; Neuron; Oxidative stress; ROS; Reactive oxygen species

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Córtex Cerebral / Meios de Cultivo Condicionados / Estresse Oxidativo / Canais de Cálcio Tipo L / Mitocôndrias / Neurônios Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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