Role of bone marrow macrophages in controlling homeostasis and repair in bone and bone marrow niches.
Semin Cell Dev Biol
; 61: 12-21, 2017 01.
Article
em En
| MEDLINE
| ID: mdl-27521519
ABSTRACT
Macrophages, named for their phagocytic ability, participate in homeostasis, tissue regeneration and inflammatory responses. Bone and adjacent marrow contain multiple functionally unique resident tissue macrophage subsets which maintain and regulate anatomically distinct niche environments within these interconnected tissues. Three subsets of bone-bone marrow resident tissue macrophages have been characterised; erythroblastic island macrophages, haematopoietic stem cell niche macrophages and osteal macrophages. The role of these macrophages in controlling homeostasis and repair in bone and bone marrow niches is reviewed in detail.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Cicatrização
/
Osso e Ossos
/
Medula Óssea
/
Nicho de Células-Tronco
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Homeostase
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Macrófagos
Limite:
Animals
/
Humans
Idioma:
En
Ano de publicação:
2017
Tipo de documento:
Article