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Mitotic MELK-eIF4B signaling controls protein synthesis and tumor cell survival.
Wang, Yubao; Begley, Michael; Li, Qing; Huang, Hai-Tsang; Lako, Ana; Eck, Michael J; Gray, Nathanael S; Mitchison, Timothy J; Cantley, Lewis C; Zhao, Jean J.
Afiliação
  • Wang Y; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Begley M; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215; Department of Systems Biology, Harvard Medical School, Boston, MA 02115;
  • Li Q; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Huang HT; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Lako A; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Eck MJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Gray NS; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;
  • Mitchison TJ; Department of Systems Biology, Harvard Medical School, Boston, MA 02115;
  • Cantley LC; Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215; Department of Systems Biology, Harvard Medical School, Boston, MA 02115; Meyer Cancer Center, Department of Medicine, Weill Cornell Medical College, New York, NY 10065 cantley@med.cornell.edu jean_zhao@dfci.harvard.edu.
  • Zhao JJ; Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115; cantley@med.cornell.edu jean_zhao@dfci.harvard.edu.
Proc Natl Acad Sci U S A ; 113(35): 9810-5, 2016 08 30.
Article em En | MEDLINE | ID: mdl-27528663
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Proteínas Serina-Treonina Quinases / Fatores de Iniciação em Eucariotos / Proteína de Sequência 1 de Leucemia de Células Mieloides / Mitose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Biossíntese de Proteínas / Proteínas Serina-Treonina Quinases / Fatores de Iniciação em Eucariotos / Proteína de Sequência 1 de Leucemia de Células Mieloides / Mitose Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article