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PARP3 is a sensor of nicked nucleosomes and monoribosylates histone H2B(Glu2).
Grundy, Gabrielle J; Polo, Luis M; Zeng, Zhihong; Rulten, Stuart L; Hoch, Nicolas C; Paomephan, Pathompong; Xu, Yingqi; Sweet, Steve M; Thorne, Alan W; Oliver, Antony W; Matthews, Steve J; Pearl, Laurence H; Caldecott, Keith W.
Afiliação
  • Grundy GJ; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Polo LM; Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Zeng Z; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Rulten SL; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Hoch NC; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Paomephan P; CAPES Foundation, Ministry of Education of Brazil, Brasilia/DF 70040-020, Brazil.
  • Xu Y; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Sweet SM; Cross-faculty NMR centre, Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK.
  • Thorne AW; Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Oliver AW; Institute of Biomedical and Biomolecular Sciences, University of Portsmouth, St Michael's Building, Portsmouth PO1 2DT, UK.
  • Matthews SJ; Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
  • Pearl LH; Cross-faculty NMR centre, Department of Life Sciences, Faculty of Natural Sciences, Imperial College London, London SW7 2AZ, UK.
  • Caldecott KW; Cancer Research UK DNA Repair Enzymes Group, Genome Damage and Stability Centre, School of Life Sciences, University of Sussex, Science Park Road, Falmer, Brighton BN1 9RQ, UK.
Nat Commun ; 7: 12404, 2016 08 17.
Article em En | MEDLINE | ID: mdl-27530147

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribose / Histonas / Nucleossomos / Poli(ADP-Ribose) Polimerases / Quebras de DNA de Cadeia Simples Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribose / Histonas / Nucleossomos / Poli(ADP-Ribose) Polimerases / Quebras de DNA de Cadeia Simples Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article