Dihydrotestosterone synthesis pathways from inactive androgen 5&#945;-androstane-3ß,17ß-diol in prostate cancer cells: Inhibition of intratumoural 3ß-hydroxysteroid dehydrogenase activities by abiraterone.

Ando, Takashi; Nishiyama, Tsutomu; Takizawa, Itsuhiro; Ishizaki, Fumio; Miyashiro, Yoshimichi; Takeda, Keisuke; Hara, Noboru; Tomita, Yoshihiko

Dihydrotestosterone synthesis pathways from inactive androgen 5α-androstane-3ß,17ß-diol in prostate cancer cells: Inhibition of intratumoural 3ß-hydroxysteroid dehydrogenase activities by abiraterone.

Ando, Takashi; Nishiyama, Tsutomu; Takizawa, Itsuhiro; Ishizaki, Fumio; Miyashiro, Yoshimichi; Takeda, Keisuke; Hara, Noboru; Tomita, Yoshihiko.

Afiliação

Ando T; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Nishiyama T; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Takizawa I; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Ishizaki F; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Miyashiro Y; ASKA Pharmaceutical medical Co. Ltd., Kawasaki, 213-8522, Japan.
Takeda K; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Hara N; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.
Tomita Y; Niigata University Graduate School of Medical and Dental Sciences, Department of Regenerative and Transplant Medicine, Niigata, 951-8510, Japan.

Sci Rep ; 6: 32198, 2016 08 26.

Article em En | MEDLINE | ID: mdl-27561382

Assuntos

3-Hidroxiesteroide Desidrogenases/antagonistas & inibidores; Androstano-3,17-diol/metabolismo; Androstenos/farmacologia; Di-Hidrotestosterona/metabolismo; Inibidores Enzimáticos/farmacologia; Proteínas de Neoplasias/antagonistas & inibidores; Neoplasias da Próstata/metabolismo; 3-Hidroxiesteroide Desidrogenases/genética; 3-Hidroxiesteroide Desidrogenases/metabolismo; Linhagem Celular Tumoral; Humanos; Masculino; Proteínas de Neoplasias/genética; Proteínas de Neoplasias/metabolismo; Neoplasias da Próstata/genética; Neoplasias da Próstata/patologia

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Próstata / Di-Hidrotestosterona / Inibidores Enzimáticos / 3-Hidroxiesteroide Desidrogenases / Androstano-3,17-diol / Androstenos / Proteínas de Neoplasias Limite: Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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