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Lipophilic 2'-O-Acetal Ester RNAs: Synthesis, Thermal Duplex Stability, Nuclease Resistance, Cellular Uptake, and siRNA Activity after Spontaneous Naked Delivery.
Biscans, Annabelle; Bertrand, Jean-Rémi; Dubois, Josephine; Rüger, Jacqueline; Vasseur, Jean-Jacques; Sczakiel, Georg; Dupouy, Christelle; Debart, Françoise.
Afiliação
  • Biscans A; IBMM, UMR 5247 CNRS, Université Montpellier, ENSCM, Campus Triolet, Place Eugène Bataillon, 34095, Montpellier Cedex 05, France.
  • Bertrand JR; UMR 8203 CNRS, Université Paris-Sud, Gustave Roussy, Université Paris-Saclay, 114 rue Edouard Vaillant, 94805, Villejuif Cedex, France.
  • Dubois J; Institut für Molekulare Medizin, Universitätsklinikum Schleswig-Holstein, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
  • Rüger J; Institut für Molekulare Medizin, Universitätsklinikum Schleswig-Holstein, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany.
  • Vasseur JJ; IBMM, UMR 5247 CNRS, Université Montpellier, ENSCM, Campus Triolet, Place Eugène Bataillon, 34095, Montpellier Cedex 05, France.
  • Sczakiel G; Institut für Molekulare Medizin, Universitätsklinikum Schleswig-Holstein, Universität zu Lübeck, Ratzeburger Allee 160, 23538, Lübeck, Germany. sczakiel@imm.uni-luebeck.de.
  • Dupouy C; IBMM, UMR 5247 CNRS, Université Montpellier, ENSCM, Campus Triolet, Place Eugène Bataillon, 34095, Montpellier Cedex 05, France.
  • Debart F; IBMM, UMR 5247 CNRS, Université Montpellier, ENSCM, Campus Triolet, Place Eugène Bataillon, 34095, Montpellier Cedex 05, France. francoise.debart@umontpellier.fr.
Chembiochem ; 17(21): 2054-2062, 2016 11 03.
Article em En | MEDLINE | ID: mdl-27569765
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Temperatura / Sistemas de Liberação de Medicamentos / Estabilidade de RNA / RNA Interferente Pequeno / Ésteres Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ribonucleases / Temperatura / Sistemas de Liberação de Medicamentos / Estabilidade de RNA / RNA Interferente Pequeno / Ésteres Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article