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PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder.
Brown, Anna; Patel, Siddharth; Ward, Carl; Lorenz, Anna; Ortiz, Mauren; DuRoss, Allison; Wieghardt, Fabian; Esch, Amanda; Otten, Elsje G; Heiser, Laura M; Korolchuk, Viktor I; Sun, Conroy; Sarkar, Sovan; Sahay, Gaurav.
Afiliação
  • Brown A; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Patel S; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Ward C; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
  • Lorenz A; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Ortiz M; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
  • DuRoss A; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Wieghardt F; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Esch A; Department of Biomedical Engineering, Collaborative Life Science Building, Oregon Health Science University, Portland OR, USA.
  • Otten EG; Institute for Cell and Molecular Biosciences, Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, United Kingdom.
  • Heiser LM; Department of Biomedical Engineering, Collaborative Life Science Building, Oregon Health Science University, Portland OR, USA.
  • Korolchuk VI; Institute for Cell and Molecular Biosciences, Newcastle University Institute for Ageing, Campus for Ageing and Vitality, Newcastle University, Newcastle upon Tyne NE4 5PL, United Kingdom.
  • Sun C; Department of Pharmaceutical Sciences, College of Pharmacy, Collaborative Life Science Building, Oregon State University, Portland OR, USA.
  • Sarkar S; Department of Radiation Medicine, School of Medicine, Oregon Health Science University, Portland OR, USA.
  • Sahay G; Institute of Cancer and Genomic Sciences, Institute of Biomedical Research, College of Medical and Dental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Sci Rep ; 6: 31750, 2016 08 30.
Article em En | MEDLINE | ID: mdl-27572704

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidiletanolaminas / Polietilenoglicóis / Solventes / Colesterol / Doença de Niemann-Pick Tipo C / Micelas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosfatidiletanolaminas / Polietilenoglicóis / Solventes / Colesterol / Doença de Niemann-Pick Tipo C / Micelas Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article