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Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution.
Liu, Zhanglong; Huang, Xi; Hu, Lingna; Pham, Linh; Poole, Katye M; Tang, Yan; Mahon, Brian P; Tang, Wenxing; Li, Kunhua; Goldfarb, Nathan E; Dunn, Ben M; McKenna, Robert; Fanucci, Gail E.
Afiliação
  • Liu Z; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and.
  • Huang X; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and.
  • Hu L; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and.
  • Pham L; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and.
  • Poole KM; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Tang Y; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Mahon BP; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Tang W; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Li K; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and.
  • Goldfarb NE; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Dunn BM; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • McKenna R; the Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, Florida 32610.
  • Fanucci GE; From the Department of Chemistry, University of Florida, Gainesville, Florida 32611 and fanucci@chem.ufl.edu.
J Biol Chem ; 291(43): 22741-22756, 2016 Oct 21.
Article em En | MEDLINE | ID: mdl-27576689
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Protease de HIV / HIV-1 / Evolução Molecular / Mutação de Sentido Incorreto / Simulação de Dinâmica Molecular Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polimorfismo Genético / Protease de HIV / HIV-1 / Evolução Molecular / Mutação de Sentido Incorreto / Simulação de Dinâmica Molecular Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article