A +1 ribosomal frameshifting motif prevalent among plant amalgaviruses.
Virology
; 498: 201-208, 2016 11.
Article
em En
| MEDLINE
| ID: mdl-27596539
ABSTRACT
Sequence accessions attributable to novel plant amalgaviruses have been found in the Transcriptome Shotgun Assembly database. Sixteen accessions, derived from 12 different plant species, appear to encompass the complete protein-coding regions of the proposed amalgaviruses, which would substantially expand the size of genus Amalgavirus from 4 current species. Other findings include evidence for UUU_CGN as a +1 ribosomal frameshifting motif prevalent among plant amalgaviruses; for a variant version of this motif found thus far in only two amalgaviruses from solanaceous plants; for a region of α-helical coiled coil propensity conserved in a central region of the ORF1 translation product of plant amalgaviruses; and for conserved sequences in a C-terminal region of the ORF2 translation product (RNA-dependent RNA polymerase) of plant amalgaviruses, seemingly beyond the region of conserved polymerase motifs. These results additionally illustrate the value of mining the TSA database and others for novel viral sequences for comparative analyses.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Vírus de Plantas
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RNA Mensageiro
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RNA Viral
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Mudança da Fase de Leitura do Gene Ribossômico
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Motivos de Nucleotídeos
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article