Production of optically active esters and alcohols from racemic alcohols by lipase-catalyzed stereoselective transesterification in non-aqueous reaction system.
J Biochem
; 105(4): 510-2, 1989 Apr.
Article
em En
| MEDLINE
| ID: mdl-2760012
ABSTRACT
Microbial lipase-catalyzed transesterification between vinyl acetate and (RS)-2-octanol or (RS)-1-phenylethanol was investigated in a reaction system without addition of aqueous or organic solvents. From a screening test with various lipases, it was found that the enzymes from Pseudomonas species could efficiently catalyze the reaction, and R-enantiomers of the racemic alcohols were preferentially esterified by them. Enantiomeric purities of the optically active alcohols (S) and esters (R) obtained from (RS)-1-phenylethanol by the stereoselective transesterification of these lipases were all more than 95%.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Álcoois
/
Lipase
Idioma:
En
Ano de publicação:
1989
Tipo de documento:
Article