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Regional glutamine deficiency in tumours promotes dedifferentiation through inhibition of histone demethylation.
Pan, Min; Reid, Michael A; Lowman, Xazmin H; Kulkarni, Rajan P; Tran, Thai Q; Liu, Xiaojing; Yang, Ying; Hernandez-Davies, Jenny E; Rosales, Kimberly K; Li, Haiqing; Hugo, Willy; Song, Chunying; Xu, Xiangdong; Schones, Dustin E; Ann, David K; Gradinaru, Viviana; Lo, Roger S; Locasale, Jason W; Kong, Mei.
Afiliação
  • Pan M; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Reid MA; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Lowman XH; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Kulkarni RP; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Tran TQ; Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California 90095, USA.
  • Liu X; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Yang Y; Department of Pharmacology and Cancer Biology, Duke University Medical School, Durham, North Carolina 27710, USA.
  • Hernandez-Davies JE; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Rosales KK; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Li H; Department of Cancer Biology, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Hugo W; Department of Information Sciences, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Song C; Division of Dermatology, Department of Medicine, David Geffen School of Medicine and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California 90095, USA.
  • Xu X; Division of Dermatology, Department of Medicine, David Geffen School of Medicine and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California 90095, USA.
  • Schones DE; Department of Pathology, University of California San Diego, La Jolla, California 92093, USA.
  • Ann DK; Department of Diabetes and Metabolic Disease, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Gradinaru V; Department of Diabetes and Metabolic Disease, Beckman Research Institute of City of Hope Cancer Center, Duarte, California 91010, USA.
  • Lo RS; Division of Biology and Biological Engineering, California Institute of Technology, Pasadena, California 91125, USA.
  • Locasale JW; Division of Dermatology, Department of Medicine, David Geffen School of Medicine and Jonsson Comprehensive Cancer Center, University of California Los Angeles, Los Angeles, California 90095, USA.
  • Kong M; Department of Pharmacology and Cancer Biology, Duke University Medical School, Durham, North Carolina 27710, USA.
Nat Cell Biol ; 18(10): 1090-101, 2016 10.
Article em En | MEDLINE | ID: mdl-27617932
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Metilação de DNA / Histona Desmetilases / Metiltransferases / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Metilação de DNA / Histona Desmetilases / Metiltransferases / Neoplasias Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article