Chronic exposure to K<sub>ATP</sub> channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons.

Haythorne, Elizabeth; Hamilton, D Lee; Findlay, John A; Beall, Craig; McCrimmon, Rory J; Ashford, Michael L J

Chronic exposure to K_ATP channel openers results in attenuated glucose sensing in hypothalamic GT1-7 neurons.

Haythorne, Elizabeth; Hamilton, D Lee; Findlay, John A; Beall, Craig; McCrimmon, Rory J; Ashford, Michael L J.

Afiliação

Haythorne E; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: e.haythorne@imperial.ac.uk.
Hamilton DL; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: d.l.hamilton@stir.ac.uk.
Findlay JA; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: J.A.Findlay@soton.ac.uk.
Beall C; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: C.Beall@exeter.ac.uk.
McCrimmon RJ; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: r.mccrimmon@dundee.ac.uk.
Ashford ML; Division of Molecular and Clinical Medicine, School of Medicine, Ninewells Hospital & Medical School, University of Dundee, Dundee, UK. Electronic address: m.l.j.ashford@dundee.ac.uk.

Neuropharmacology ; 111: 212-222, 2016 12.

Article em En | MEDLINE | ID: mdl-27618741

Assuntos

Compostos Bicíclicos Heterocíclicos com Pontes/farmacologia; Óxidos S-Cíclicos/farmacologia; Glucose/metabolismo; Hipoglicemia/metabolismo; Hipotálamo/efeitos dos fármacos; Canais KATP/metabolismo; Neurônios/efeitos dos fármacos; Potenciais de Ação/efeitos dos fármacos; Animais; Compostos Bicíclicos Heterocíclicos com Pontes/farmacocinética; Linhagem Celular; Óxidos S-Cíclicos/farmacocinética; Glucose/farmacologia; Hipotálamo/metabolismo; Canais KATP/agonistas; Camundongos; Neurônios/metabolismo

Palavras-chave

Diazoxide; Diazoxide (PubChem CID: 3019); Glucose sensing; Hypoglycemia; K(ATP); NN414; NN414 (Tifenazoxide) (PubChem CID 219048); Type 1 diabetes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Compostos Bicíclicos Heterocíclicos com Pontes / Óxidos S-Cíclicos / Canais KATP / Glucose / Hipoglicemia / Hipotálamo / Neurônios Limite: Animals Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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