Transcranial magnetic stimulation combined with upper-limb training for improving function after stroke: A systematic review and meta-analysis.
J Neurol Sci
; 369: 149-158, 2016 Oct 15.
Article
em En
| MEDLINE
| ID: mdl-27653882
ABSTRACT
BACKGROUND:
Several neuromodulation treatments have been developed, and their effects have been studied in recent years in order to improve neurological rehabilitation after a stroke. The association between upper-limb training and repetitive transcranial magnetic stimulation (rTMS) has provoked controversies and produced inconclusive results.OBJECTIVE:
The purpose of this study was to investigate the effects of rTMS combined with upper-limb training versus sham rTMS combined with upper-limb training on the upper-limb recovery after a stroke.METHODS:
A systematic review with meta-analysis was performed. The eligible studies were randomized controlled trials with stroke subjects, and the outcomes were related to upper-limb motor/functional status and spasticity.RESULTS:
A total of 3234 citations were identified, and 11 studies were included. The meta-analysis included eight studies with 199 participants and did not show any difference between groups, neither for upper-limb function nor for spasticity (upper-limb function [0.03 (95% CI -0.25 to 0.32; I(2) 0%)] and Modified Ashworth Scale [-0.31 (95% CI -0.78 to 0.17; I(2) 43%)]).CONCLUSION:
The current state of the literature is not enough to support the hypothesis that a combination of rTMS and upper-limb training has a stronger effect on upper-limb function than upper-limb training alone.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Exercício Físico
/
Acidente Vascular Cerebral
/
Extremidade Superior
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Estimulação Magnética Transcraniana
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Reabilitação do Acidente Vascular Cerebral
Tipo de estudo:
Clinical_trials
/
Systematic_reviews
Limite:
Humans
Idioma:
En
Ano de publicação:
2016
Tipo de documento:
Article