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Age-related accrual of methylomic variability is linked to fundamental ageing mechanisms.
Slieker, Roderick C; van Iterson, Maarten; Luijk, René; Beekman, Marian; Zhernakova, Daria V; Moed, Matthijs H; Mei, Hailiang; van Galen, Michiel; Deelen, Patrick; Bonder, Marc Jan; Zhernakova, Alexandra; Uitterlinden, André G; Tigchelaar, Ettje F; Stehouwer, Coen D A; Schalkwijk, Casper G; van der Kallen, Carla J H; Hofman, Albert; van Heemst, Diana; de Geus, Eco J; van Dongen, Jenny; Deelen, Joris; van den Berg, Leonard H; van Meurs, Joyce; Jansen, Rick; 't Hoen, Peter A C; Franke, Lude; Wijmenga, Cisca; Veldink, Jan H; Swertz, Morris A; van Greevenbroek, Marleen M J; van Duijn, Cornelia M; Boomsma, Dorret I; Slagboom, P Eline; Heijmans, Bastiaan T.
Afiliação
  • Slieker RC; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • van Iterson M; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Luijk R; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Beekman M; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Zhernakova DV; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Moed MH; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Mei H; Sequence Analysis Support Core, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • van Galen M; Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Deelen P; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Bonder MJ; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Zhernakova A; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Uitterlinden AG; Department of Internal Medicine, Erasmus University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
  • Tigchelaar EF; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Stehouwer CD; Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
  • Schalkwijk CG; Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
  • van der Kallen CJ; Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
  • Hofman A; Department of Epidemiology, Erasmus University Medical Center, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
  • van Heemst D; Department of Gerontology and Geriatrics, Leiden University Medical Center, Albinusdreef 2, 2333 ZA, Leiden, The Netherlands.
  • de Geus EJ; Department of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.
  • van Dongen J; Department of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.
  • Deelen J; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • van den Berg LH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
  • van Meurs J; Department of Internal Medicine, Erasmus University Medical Center, Wytemaweg 80, 3015 CN, Rotterdam, The Netherlands.
  • Jansen R; Department of Psychiatry, VU University Medical Center, Neuroscience Campus Amsterdam, A.J. Ernststraat 1187, 1081 HL, Amsterdam, The Netherlands.
  • 't Hoen PA; Department of Human Genetics, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Franke L; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Wijmenga C; Department of Genetics, University Medical Centre Groningen, Antonius Deusinglaan 1, 9713 AV, Groningen, The Netherlands.
  • Veldink JH; Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Universiteitsweg 100, 3584 CG, Utrecht, The Netherlands.
  • Swertz MA; Genomics Coordination Center, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.
  • van Greevenbroek MM; Department of Internal Medicine and School for Cardiovascular Diseases (CARIM), Maastricht University Medical Center, Universiteitssingel 50, 6229 ER, Maastricht, The Netherlands.
  • van Duijn CM; Department of Genetic Epidemiology, Erasmus University Medical Center, Dr. Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands.
  • Boomsma DI; Department of Biological Psychology, VU University Amsterdam, Neuroscience Campus Amsterdam, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands.
  • Slagboom PE; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands.
  • Heijmans BT; Molecular Epidemiology section, Leiden University Medical Center, Einthovenweg 20, 2333 ZC, Leiden, The Netherlands. bas.heijmans@lumc.nl.
Genome Biol ; 17(1): 191, 2016 Sep 22.
Article em En | MEDLINE | ID: mdl-27654999
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Ano de publicação: 2016 Tipo de documento: Article