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Structure-guided enzymology of the lipid A acyltransferase LpxM reveals a dual activity mechanism.
Dovala, Dustin; Rath, Christopher M; Hu, Qijun; Sawyer, William S; Shia, Steven; Elling, Robert A; Knapp, Mark S; Metzger, Louis E.
Afiliação
  • Dovala D; Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Rath CM; Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Hu Q; Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Sawyer WS; Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Shia S; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Elling RA; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Knapp MS; Global Discovery Chemistry, Novartis Institutes for BioMedical Research, Emeryville, CA 94608.
  • Metzger LE; Infectious Diseases, Novartis Institutes for BioMedical Research, Emeryville, CA 94608; louis.metzger_iv@novartis.com.
Proc Natl Acad Sci U S A ; 113(41): E6064-E6071, 2016 10 11.
Article em En | MEDLINE | ID: mdl-27681620
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aciltransferases / Lipídeo A Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Aciltransferases / Lipídeo A Tipo de estudo: Prognostic_studies Idioma: En Ano de publicação: 2016 Tipo de documento: Article