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Ataluren stimulates ribosomal selection of near-cognate tRNAs to promote nonsense suppression.
Roy, Bijoyita; Friesen, Westley J; Tomizawa, Yuki; Leszyk, John D; Zhuo, Jin; Johnson, Briana; Dakka, Jumana; Trotta, Christopher R; Xue, Xiaojiao; Mutyam, Venkateshwar; Keeling, Kim M; Mobley, James A; Rowe, Steven M; Bedwell, David M; Welch, Ellen M; Jacobson, Allan.
Afiliação
  • Roy B; Department of Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655-0122.
  • Friesen WJ; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Tomizawa Y; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Leszyk JD; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Zhuo J; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01655-0122.
  • Johnson B; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Dakka J; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Trotta CR; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Xue X; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Mutyam V; PTC Therapeutics Inc., South Plainfield, NJ 07080.
  • Keeling KM; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Mobley JA; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Rowe SM; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Bedwell DM; Department of Medicine, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Welch EM; Department of Biochemistry and Molecular Genetics, University of Alabama at Birmingham, Birmingham, AL 35294.
  • Jacobson A; Gregory Fleming James Cystic Fibrosis Research Center, University of Alabama at Birmingham, Birmingham, AL 35294.
Proc Natl Acad Sci U S A ; 113(44): 12508-12513, 2016 11 01.
Article em En | MEDLINE | ID: mdl-27702906
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Ribossomos / RNA de Transferência / Códon sem Sentido Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxidiazóis / Ribossomos / RNA de Transferência / Códon sem Sentido Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article