Nanoscale Coordination Polymers Codeliver Carboplatin and Gemcitabine for Highly Effective Treatment of Platinum-Resistant Ovarian Cancer.

Poon, Christopher; Duan, Xiaopin; Chan, Christina; Han, Wenbo; Lin, Wenbin

Poon, Christopher; Duan, Xiaopin; Chan, Christina; Han, Wenbo; Lin, Wenbin.

Afiliação

Poon C; Department of Chemistry, University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Duan X; Department of Chemistry, University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Chan C; Department of Chemistry, University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Han W; Department of Chemistry, University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.
Lin W; Department of Chemistry, University of Chicago , 929 East 57th Street, Chicago, Illinois 60637, United States.

Mol Pharm ; 13(11): 3665-3675, 2016 11 07.

Article em En | MEDLINE | ID: mdl-27712076

Assuntos

Carboplatina/química; Carboplatina/farmacologia; Desoxicitidina/análogos & derivados; Platina/farmacologia; Polímeros/química; Protocolos de Quimioterapia Combinada Antineoplásica/química; Protocolos de Quimioterapia Combinada Antineoplásica/farmacologia; Linhagem Celular Tumoral; Desoxicitidina/química; Desoxicitidina/farmacologia; Resistencia a Medicamentos Antineoplásicos; Feminino; Humanos; Nanopartículas/química; Neoplasias Ovarianas/metabolismo; Neoplasias Ovarianas/patologia; Resultado do Tratamento; Gencitabina

Palavras-chave

carboplatin; gemcitabine; nanoscale coordination polymers; platinum-resistant ovarian cancer; synergistic effect

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Platina / Polímeros / Carboplatina / Desoxicitidina Limite: Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

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