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Fenofibrate Inhibits Cytochrome P450 Epoxygenase 2C Activity to Suppress Pathological Ocular Angiogenesis.
Gong, Yan; Shao, Zhuo; Fu, Zhongjie; Edin, Matthew L; Sun, Ye; Liegl, Raffael G; Wang, Zhongxiao; Liu, Chi-Hsiu; Burnim, Samuel B; Meng, Steven S; Lih, Fred B; SanGiovanni, John Paul; Zeldin, Darryl C; Hellström, Ann; Smith, Lois E H.
Afiliação
  • Gong Y; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Shao Z; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Fu Z; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Edin ML; Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, United States.
  • Sun Y; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Liegl RG; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Wang Z; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Liu CH; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Burnim SB; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Meng SS; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States.
  • Lih FB; Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, United States.
  • SanGiovanni JP; Section on Nutritional Neurosciences, Laboratory of Membrane Biophysics and Biochemistry, National Institute on Alcohol Abuse and Alcoholism, National Institutes of Health, Bethesda, MD 20892, United States.
  • Zeldin DC; Division of Intramural Research, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, United States.
  • Hellström A; Department of Ophthalmology, Sahlgrenska Academy at University of Gothenburg, Gothenburg 40530, Sweden.
  • Smith LEH; Department of Ophthalmology, Boston Children's Hospital, Harvard Medical School, Boston, MA 01248, United States. Electronic address: lois.smith@childrens.harvard.edu.
EBioMedicine ; 13: 201-211, 2016 Nov.
Article em En | MEDLINE | ID: mdl-27720395

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenofibrato / Neovascularização Retiniana / Neovascularização de Coroide / Inibidores da Angiogênese / Sistema Enzimático do Citocromo P-450 / Inibidores das Enzimas do Citocromo P-450 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenofibrato / Neovascularização Retiniana / Neovascularização de Coroide / Inibidores da Angiogênese / Sistema Enzimático do Citocromo P-450 / Inibidores das Enzimas do Citocromo P-450 Tipo de estudo: Etiology_studies / Prognostic_studies Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article