Limitations of the hCMEC/D3 cell line as a model for Aß clearance by the human blood-brain barrier.

Biemans, Elisanne A L M; Jäkel, Lieke; de Waal, Robert M W; Kuiperij, H Bea; Verbeek, Marcel M

Biemans, Elisanne A L M; Jäkel, Lieke; de Waal, Robert M W; Kuiperij, H Bea; Verbeek, Marcel M.

Afiliação

Biemans EALM; Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Departments of Neurology and Laboratory Medicine, Radboud Alzheimer Centre, Nijmegen, The Netherlands.
Jäkel L; Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Departments of Neurology and Laboratory Medicine, Radboud Alzheimer Centre, Nijmegen, The Netherlands.
de Waal RMW; Radboud University Medical Center, Department of Pathology, Nijmegen, The Netherlands.
Kuiperij HB; Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Departments of Neurology and Laboratory Medicine, Radboud Alzheimer Centre, Nijmegen, The Netherlands.
Verbeek MM; Radboud University Medical Center, Donders Institute for Brain, Cognition and Behaviour, Departments of Neurology and Laboratory Medicine, Radboud Alzheimer Centre, Nijmegen, The Netherlands.

J Neurosci Res ; 95(7): 1513-1522, 2017 07.

Article em En | MEDLINE | ID: mdl-27726164

Assuntos

Peptídeos beta-Amiloides/metabolismo; Barreira Hematoencefálica/citologia; Barreira Hematoencefálica/metabolismo; Fragmentos de Peptídeos/metabolismo; Junções Íntimas/metabolismo; Encéfalo/citologia; Encéfalo/metabolismo; Linhagem Celular; Humanos

Palavras-chave

amyloid-ß; blood-brain barrier; clearance; hCMEC/D3; in vitro model

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fragmentos de Peptídeos / Barreira Hematoencefálica / Peptídeos beta-Amiloides / Junções Íntimas Limite: Humans Idioma: En Ano de publicação: 2017 Tipo de documento: Article

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