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Enhanced Cytosolic Ca2+ Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias.
Xiao, Zhichao; Guo, Wenting; Sun, Bo; Hunt, Donald J; Wei, Jinhong; Liu, Yingjie; Wang, Yundi; Wang, Ruiwu; Jones, Peter P; Back, Thomas G; Chen, S R Wayne.
Afiliação
  • Xiao Z; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Guo W; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Sun B; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Hunt DJ; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Wei J; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Liu Y; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Wang Y; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Wang R; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada.
  • Jones PP; the Department of Physiology, Otago School of Medical Sciences and HeartOtago, University of Otago, Dunedin 9054, New Zealand, and.
  • Back TG; the Department of Chemistry, University of Calgary, Calgary, Alberta T2N 1N4, Canada.
  • Chen SRW; From the the Department of Physiology and Pharmacology, Libin Cardiovascular Institute of Alberta, University of Calgary, Calgary, Alberta T2N 4N1, Canada,. Electronic address: swchen@ucalgary.ca.
J Biol Chem ; 291(47): 24528-24537, 2016 Nov 18.
Article em En | MEDLINE | ID: mdl-27733687
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Cálcio / Canal de Liberação de Cálcio do Receptor de Rianodina / Sinalização do Cálcio / Mutação de Sentido Incorreto Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Arritmias Cardíacas / Cálcio / Canal de Liberação de Cálcio do Receptor de Rianodina / Sinalização do Cálcio / Mutação de Sentido Incorreto Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article