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Circumventing furin enhances factor VIII biological activity and ameliorates bleeding phenotypes in hemophilia models.
Siner, Joshua I; Samelson-Jones, Benjamin J; Crudele, Julie M; French, Robert A; Lee, Benjamin J; Zhou, Shanzhen; Merricks, Elizabeth; Raymer, Robin; Nichols, Timothy C; Camire, Rodney M; Arruda, Valder R.
Afiliação
  • Siner JI; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Samelson-Jones BJ; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Crudele JM; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • French RA; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Lee BJ; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Zhou S; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Merricks E; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
  • Raymer R; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Nichols TC; The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
  • Camire RM; University of North Carolina, Chapel Hill, North Carolina, USA.
  • Arruda VR; University of North Carolina, Chapel Hill, North Carolina, USA.
JCI Insight ; 1(16): e89371, 2016 Oct 06.
Article em En | MEDLINE | ID: mdl-27734034
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator VIII / Terapia Genética / Furina / Hemofilia A Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator VIII / Terapia Genética / Furina / Hemofilia A Tipo de estudo: Prognostic_studies Limite: Animals / Humans / Male Idioma: En Ano de publicação: 2016 Tipo de documento: Article