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Molecular basis for catalysis and substrate-mediated cellular stabilization of human tryptophan 2,3-dioxygenase.
Lewis-Ballester, Ariel; Forouhar, Farhad; Kim, Sung-Mi; Lew, Scott; Wang, YongQiang; Karkashon, Shay; Seetharaman, Jayaraman; Batabyal, Dipanwita; Chiang, Bing-Yu; Hussain, Munif; Correia, Maria Almira; Yeh, Syun-Ru; Tong, Liang.
Afiliação
  • Lewis-Ballester A; Department of Physiology and Biophysics Albert Einstein College of Medicine Bronx, NY 10461, USA.
  • Forouhar F; Department of Biological Sciences Northeast Structural Genomics Consortium Columbia University New York, NY 10027, USA.
  • Kim SM; Departments of Cellular and Molecular Pharmacology, Pharmaceutical Chemistry, and Bioengineering and Therapeutic Sciences, The Liver Center, University of California at San Francisco San Francisco, CA 94158, USA.
  • Lew S; Department of Biological Sciences Northeast Structural Genomics Consortium Columbia University New York, NY 10027, USA.
  • Wang Y; Departments of Cellular and Molecular Pharmacology, Pharmaceutical Chemistry, and Bioengineering and Therapeutic Sciences, The Liver Center, University of California at San Francisco San Francisco, CA 94158, USA.
  • Karkashon S; Department of Physiology and Biophysics Albert Einstein College of Medicine Bronx, NY 10461, USA.
  • Seetharaman J; Department of Biological Sciences Northeast Structural Genomics Consortium Columbia University New York, NY 10027, USA.
  • Batabyal D; Department of Physiology and Biophysics Albert Einstein College of Medicine Bronx, NY 10461, USA.
  • Chiang BY; Department of Physiology and Biophysics Albert Einstein College of Medicine Bronx, NY 10461, USA.
  • Hussain M; Department of Biological Sciences Northeast Structural Genomics Consortium Columbia University New York, NY 10027, USA.
  • Correia MA; Departments of Cellular and Molecular Pharmacology, Pharmaceutical Chemistry, and Bioengineering and Therapeutic Sciences, The Liver Center, University of California at San Francisco San Francisco, CA 94158, USA.
  • Yeh SR; Department of Physiology and Biophysics Albert Einstein College of Medicine Bronx, NY 10461, USA.
  • Tong L; Department of Biological Sciences Northeast Structural Genomics Consortium Columbia University New York, NY 10027, USA.
Sci Rep ; 6: 35169, 2016 10 20.
Article em En | MEDLINE | ID: mdl-27762317
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Triptofano / Triptofano Oxigenase / Estrutura Secundária de Proteína / Indolamina-Pirrol 2,3,-Dioxigenase Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oxigênio / Triptofano / Triptofano Oxigenase / Estrutura Secundária de Proteína / Indolamina-Pirrol 2,3,-Dioxigenase Limite: Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article