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Tuberculosis: An Infection-Initiated Autoimmune Disease?
Elkington, Paul; Tebruegge, Marc; Mansour, Salah.
Afiliação
  • Elkington P; NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK. Electronic address: p.elkington@soton.ac.uk.
  • Tebruegge M; NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
  • Mansour S; NIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences Academic Unit, Faculty of Medicine, University of Southampton, Southampton, UK.
Trends Immunol ; 37(12): 815-818, 2016 12.
Article em En | MEDLINE | ID: mdl-27773684
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (Mtb) and provided original proof that an infectious agent can cause human disease. However, key steps in TB pathogenesis remain poorly understood. We propose that autoimmunity is a critical and overlooked process driving pathology in TB, and present clinical and experimental observations supporting this hypothesis.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doenças Autoimunes / Tuberculose / Mycobacterium tuberculosis Limite: Animals / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article