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PIM1 kinase inhibition as a targeted therapy against triple-negative breast tumors with elevated MYC expression.
Horiuchi, Dai; Camarda, Roman; Zhou, Alicia Y; Yau, Christina; Momcilovic, Olga; Balakrishnan, Sanjeev; Corella, Alexandra N; Eyob, Henok; Kessenbrock, Kai; Lawson, Devon A; Marsh, Lindsey A; Anderton, Brittany N; Rohrberg, Julia; Kunder, Ratika; Bazarov, Alexey V; Yaswen, Paul; McManus, Michael T; Rugo, Hope S; Werb, Zena; Goga, Andrei.
Afiliação
  • Horiuchi D; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Camarda R; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California, USA.
  • Zhou AY; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Yau C; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA.
  • Momcilovic O; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Balakrishnan S; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Corella AN; Department of Surgery, University of California, San Francisco, San Francisco, California, USA.
  • Eyob H; Cancer and Developmental Therapeutics Program, Buck Institute for Research on Aging, Novato, California, USA.
  • Kessenbrock K; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Lawson DA; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Marsh LA; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Anderton BN; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Rohrberg J; Department of Anatomy, University of California, San Francisco, San Francisco, California, USA.
  • Kunder R; Department of Anatomy, University of California, San Francisco, San Francisco, California, USA.
  • Bazarov AV; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Yaswen P; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA.
  • McManus MT; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Rugo HS; Department of Cell and Tissue Biology, University of California, San Francisco (UCSF), San Francisco, California, USA.
  • Werb Z; Department of Pharmacology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Goga A; Robert H. Lurie Comprehensive Cancer Center, Northwestern University, Chicago, Illinois, USA.
Nat Med ; 22(11): 1321-1329, 2016 11.
Article em En | MEDLINE | ID: mdl-27775705
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Carcinoma Ductal de Mama / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-pim-1 / Neoplasias de Mama Triplo Negativas / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Proto-Oncogênicas c-myc / Carcinoma Ductal de Mama / Inibidores de Proteínas Quinases / Proteínas Proto-Oncogênicas c-pim-1 / Neoplasias de Mama Triplo Negativas / Neoplasias Mamárias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Ano de publicação: 2016 Tipo de documento: Article