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Discovery, structure-activity relationship studies, and anti-nociceptive effects of N-(1,2,3,4-tetrahydro-1-isoquinolinylmethyl)benzamides as novel opioid receptor agonists.
Chen, Sheng-Ren; Ke, Yi-Yu; Yeh, Teng-Kuang; Lin, Shu-Yu; Ou, Li-Chin; Chen, Shu-Chun; Chang, Wan-Ting; Chang, Hsiao-Fu; Wu, Zih-Huei; Hsieh, Chih-Chien; Law, Ping-Yee; Loh, Horace H; Shih, Chuan; Lai, Yiu-Kay; Yeh, Shiu-Hwa; Ueng, Shau-Hua.
Afiliação
  • Chen SR; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan; Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan.
  • Ke YY; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Yeh TK; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Lin SY; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Ou LC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Chen SC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Chang WT; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Chang HF; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Wu ZH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Hsieh CC; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Law PY; Department of Pharmacology, University of Minnesota, Medical School, Minneapolis, MN, 55455, USA.
  • Loh HH; Department of Pharmacology, University of Minnesota, Medical School, Minneapolis, MN, 55455, USA.
  • Shih C; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan.
  • Lai YK; Institute of Biotechnology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan. Electronic address: yklai@life.nthu.edu.tw.
  • Yeh SH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan; The PhD Program for Neural Regenerative Medicine, Taipei Medical University, Taipei, 110, Taiwan. Electronic address: bau9763@bp.nhri.org.tw.
  • Ueng SH; Institute of Biotechnology and Pharmaceutical Research, National Health Research Institutes, Miaoli County, 35053, Taiwan. Electronic address: shueng@nhri.org.tw.
Eur J Med Chem ; 126: 202-217, 2017 Jan 27.
Article em En | MEDLINE | ID: mdl-27776274
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Opioides mu / Analgésicos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzamidas / Receptores Opioides mu / Analgésicos Limite: Animals Idioma: En Ano de publicação: 2017 Tipo de documento: Article